Rapid signal transduction in Sertoli cells
نویسندگان
چکیده
منابع مشابه
The role of calcium in signal transduction processes in Sertoli cells.
Sertoli cells play a pivotal role in regulation and maintenance of spermatogenesis. They are hormonally regulated predominantly by follicle-stimulating hormone (FSH) and testosterone (T). Although FSH and T have distinct mechanisms of action they act synergistically in promoting spermatogenesis. Stimulation of freshly isolated Sertoli cells with FSH evokes a prompt rise in cytosolic calcium whi...
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Receptor activated adenylate cyclase acts as a major transmembrane signalling system. It is widely accepted that upon binding to its receptor, follicle-stimulating hormone (FSH) activates the cAMP-dependent pathway which in turn mediates FSH-induced estradiol production in Sertoli cells. Studies utilizing several chemically derived variants of FSH have demonstrated that these variants bind to t...
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ژورنال
عنوان ژورنال: European Journal of Endocrinology
سال: 2002
ISSN: 0804-4643,1479-683X
DOI: 10.1530/eje.0.1470425